ผลต่างระหว่างรุ่นของ "ฮีตช็อกโปรตีน 47"
เนื้อหาที่ลบ เนื้อหาที่เพิ่ม
Thomson Walt (คุย | ส่วนร่วม) |
Thomson Walt (คุย | ส่วนร่วม) ลไม่มีความย่อการแก้ไข |
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| ⚫ | * {{cite journal | vauthors = Razzaque MS, Taguchi T | title = The possible role of colligin/HSP47, a collagen-binding protein, in the pathogenesis of human and experimental fibrotic diseases | journal = Histology and Histopathology | volume = 14 | issue = 4 | pages = 1199–212 | date = October 1999 | pmid = 10506936 | doi = }} |
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| ⚫ | * {{cite journal | vauthors = Clarke EP, Sanwal BD | title = Cloning of a human collagen-binding protein, and its homology with rat gp46, chick hsp47 and mouse J6 proteins | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1129 | issue = 2 | pages = 246–8 | date = January 1992 | pmid = 1309665 | doi = 10.1016/0167-4781(92)90498-o }} |
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| ⚫ | * {{cite journal | vauthors = Ikegawa S, Sudo K, Okui K, Nakamura Y | title = Isolation, characterization and chromosomal assignment of human colligin-2 gene (CBP2) | journal = Cytogenetics and Cell Genetics | volume = 71 | issue = 2 | pages = 182–6 | year = 1995 | pmid = 7656593 | doi = 10.1159/000134103 }} |
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| ⚫ | * {{cite journal | vauthors = Bekri S, Adélaïde J, Merscher S, Grosgeorge J, Caroli-Bosc F, Perucca-Lostanlen D, Kelley PM, Pébusque MJ, Theillet C, Birnbaum D, Gaudray P | title = Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma | journal = Cytogenetics and Cell Genetics | volume = 79 | issue = 1–2 | pages = 125–31 | year = 1998 | pmid = 9533029 | doi = 10.1159/000134699 }} |
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| ⚫ | * {{cite journal | vauthors = Hattori T, Fujisawa T, Sasaki K, Yutani Y, Nakanishi T, Takahashi K, Takigawa M | title = Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8) | journal = Biochemical and Biophysical Research Communications | volume = 245 | issue = 3 | pages = 679–83 | date = April 1998 | pmid = 9588174 | doi = 10.1006/bbrc.1998.8505 }} |
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| ⚫ | * {{cite journal | vauthors = Nagai N, Tetuya Y, Hosokawa N, Nagata K | title = The human genome has only one functional hsp47 gene (CBP2) and a pseudogene (pshsp47) | journal = Gene | volume = 227 | issue = 2 | pages = 241–8 | date = February 1999 | pmid = 10023073 | doi = 10.1016/S0378-1119(98)00592-7 }} |
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| ⚫ | * {{cite journal | vauthors = Hebert C, Norris K, Della Coletta R, Reynolds M, Ordóñez J, Sauk JJ | title = Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines | journal = Journal of Cellular Biochemistry | volume = 73 | issue = 2 | pages = 248–58 | date = May 1999 | pmid = 10227388 | doi = 10.1002/(SICI)1097-4644(19990501)73:2<248::AID-JCB11>3.0.CO;2-A }} |
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| ⚫ | * {{cite journal | vauthors = Koide T, Aso A, Yorihuzi T, Nagata K | title = Conformational requirements of collagenous peptides for recognition by the chaperone protein HSP47 | journal = The Journal of Biological Chemistry | volume = 275 | issue = 36 | pages = 27957–63 | date = September 2000 | pmid = 10862616 | doi = 10.1074/jbc.M003026200 | doi-access = free }} |
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| ⚫ | * {{cite journal | vauthors = Hattori T, Takahash K, Yutani Y, Fujisawa T, Nakanishi T, Takigawa M | title = Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47 | journal = Journal of Bone and Mineral Metabolism | volume = 18 | issue = 6 | pages = 328–34 | year = 2001 | pmid = 11052465 | doi = 10.1007/s007740070004 | s2cid = 35696096 }} |
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| ⚫ | * {{cite journal | vauthors = Pelletier G, Stefanovsky VY, Faubladier M, Hirschler-Laszkiewicz I, Savard J, Rothblum LI, Côté J, Moss T | title = Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription | journal = Molecular Cell | volume = 6 | issue = 5 | pages = 1059–66 | date = November 2000 | pmid = 11106745 | doi = 10.1016/S1097-2765(00)00104-0 }} |
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| ⚫ | * {{cite journal | vauthors = Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K | title = Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences | journal = Biochemical and Biophysical Research Communications | volume = 280 | issue = 2 | pages = 535–40 | date = January 2001 | pmid = 11162551 | doi = 10.1006/bbrc.2000.4149 }} |
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| ⚫ | * {{cite journal | vauthors = Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN | title = TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription | journal = The Journal of Biological Chemistry | volume = 276 | issue = 48 | pages = 44633–40 | date = November 2001 | pmid = 11572868 | doi = 10.1074/jbc.M107466200 | doi-access = free }} |
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| ⚫ | * {{cite journal | vauthors = Song CZ, Keller K, Murata K, Asano H, Stamatoyannopoulos G|authorlink5=George Stamatoyannopoulos | title = Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 9 | pages = 7029–36 | date = March 2002 | pmid = 11748222 | pmc = 2808425 | doi = 10.1074/jbc.M108826200 }} |
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| ⚫ | * {{cite journal | vauthors = Sasaki H, Sato T, Yamauchi N, Okamoto T, Kobayashi D, Iyama S, Kato J, Matsunaga T, Takimoto R, Takayama T, Kogawa K, Watanabe N, Niitsu Y | title = Induction of heat shock protein 47 synthesis by TGF-beta and IL-1 beta via enhancement of the heat shock element binding activity of heat shock transcription factor 1 | journal = Journal of Immunology | volume = 168 | issue = 10 | pages = 5178–83 | date = May 2002 | pmid = 11994473 | doi = 10.4049/jimmunol.168.10.5178 | doi-access = free }} |
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| ⚫ | * {{cite journal | vauthors = Razzaque MS, Ahmed AR | title = Collagens, collagen-binding heat shock protein 47 and transforming growth factor-beta 1 are induced in cicatricial pemphigoid: possible role(s) in dermal fibrosis | journal = Cytokine | volume = 17 | issue = 6 | pages = 311–6 | date = March 2002 | pmid = 12061838 | doi = 10.1006/cyto.2002.1020 }} |
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| ⚫ | * {{cite journal | vauthors = Sato K, Yomogida K, Wada T, Yorihuzi T, Nishimune Y, Hosokawa N, Nagata K | title = Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary | journal = The Journal of Biological Chemistry | volume = 277 | issue = 40 | pages = 37678–84 | date = October 2002 | pmid = 12145293 | doi = 10.1074/jbc.M205347200 | doi-access = free }} |
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| ⚫ | * {{cite journal | vauthors = Rocnik EF, van der Veer E, Cao H, Hegele RA, Pickering JG | title = Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells | journal = The Journal of Biological Chemistry | volume = 277 | issue = 41 | pages = 38571–8 | date = October 2002 | pmid = 12163502 | doi = 10.1074/jbc.M206689200 | doi-access = free }} |
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W: [[ทริปโตเฟน]]<br /> |
W: [[ทริปโตเฟน]]<br /> |
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Y: [[ไทโรซีน]]</div>}} |
Y: [[ไทโรซีน]]</div>}} |
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| ⚫ | |||
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| ⚫ | |||
| ⚫ | |||
| ⚫ | * {{cite journal | vauthors = Razzaque MS, Taguchi T | title = The possible role of colligin/HSP47, a collagen-binding protein, in the pathogenesis of human and experimental fibrotic diseases | journal = Histology and Histopathology | volume = 14 | issue = 4 | pages = 1199–212 | date = October 1999 | pmid = 10506936 | doi = }} |
||
| ⚫ | |||
| ⚫ | * {{cite journal | vauthors = Clarke EP, Sanwal BD | title = Cloning of a human collagen-binding protein, and its homology with rat gp46, chick hsp47 and mouse J6 proteins | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1129 | issue = 2 | pages = 246–8 | date = January 1992 | pmid = 1309665 | doi = 10.1016/0167-4781(92)90498-o }} |
||
| ⚫ | * {{cite journal | vauthors = Ikegawa S, Sudo K, Okui K, Nakamura Y | title = Isolation, characterization and chromosomal assignment of human colligin-2 gene (CBP2) | journal = Cytogenetics and Cell Genetics | volume = 71 | issue = 2 | pages = 182–6 | year = 1995 | pmid = 7656593 | doi = 10.1159/000134103 }} |
||
| ⚫ | |||
| ⚫ | * {{cite journal | vauthors = Bekri S, Adélaïde J, Merscher S, Grosgeorge J, Caroli-Bosc F, Perucca-Lostanlen D, Kelley PM, Pébusque MJ, Theillet C, Birnbaum D, Gaudray P | title = Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma | journal = Cytogenetics and Cell Genetics | volume = 79 | issue = 1–2 | pages = 125–31 | year = 1998 | pmid = 9533029 | doi = 10.1159/000134699 }} |
||
| ⚫ | * {{cite journal | vauthors = Hattori T, Fujisawa T, Sasaki K, Yutani Y, Nakanishi T, Takahashi K, Takigawa M | title = Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8) | journal = Biochemical and Biophysical Research Communications | volume = 245 | issue = 3 | pages = 679–83 | date = April 1998 | pmid = 9588174 | doi = 10.1006/bbrc.1998.8505 }} |
||
| ⚫ | * {{cite journal | vauthors = Nagai N, Tetuya Y, Hosokawa N, Nagata K | title = The human genome has only one functional hsp47 gene (CBP2) and a pseudogene (pshsp47) | journal = Gene | volume = 227 | issue = 2 | pages = 241–8 | date = February 1999 | pmid = 10023073 | doi = 10.1016/S0378-1119(98)00592-7 }} |
||
| ⚫ | * {{cite journal | vauthors = Hebert C, Norris K, Della Coletta R, Reynolds M, Ordóñez J, Sauk JJ | title = Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines | journal = Journal of Cellular Biochemistry | volume = 73 | issue = 2 | pages = 248–58 | date = May 1999 | pmid = 10227388 | doi = 10.1002/(SICI)1097-4644(19990501)73:2<248::AID-JCB11>3.0.CO;2-A }} |
||
| ⚫ | * {{cite journal | vauthors = Koide T, Aso A, Yorihuzi T, Nagata K | title = Conformational requirements of collagenous peptides for recognition by the chaperone protein HSP47 | journal = The Journal of Biological Chemistry | volume = 275 | issue = 36 | pages = 27957–63 | date = September 2000 | pmid = 10862616 | doi = 10.1074/jbc.M003026200 | doi-access = free }} |
||
| ⚫ | * {{cite journal | vauthors = Hattori T, Takahash K, Yutani Y, Fujisawa T, Nakanishi T, Takigawa M | title = Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47 | journal = Journal of Bone and Mineral Metabolism | volume = 18 | issue = 6 | pages = 328–34 | year = 2001 | pmid = 11052465 | doi = 10.1007/s007740070004 | s2cid = 35696096 }} |
||
| ⚫ | * {{cite journal | vauthors = Pelletier G, Stefanovsky VY, Faubladier M, Hirschler-Laszkiewicz I, Savard J, Rothblum LI, Côté J, Moss T | title = Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription | journal = Molecular Cell | volume = 6 | issue = 5 | pages = 1059–66 | date = November 2000 | pmid = 11106745 | doi = 10.1016/S1097-2765(00)00104-0 }} |
||
| ⚫ | * {{cite journal | vauthors = Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K | title = Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences | journal = Biochemical and Biophysical Research Communications | volume = 280 | issue = 2 | pages = 535–40 | date = January 2001 | pmid = 11162551 | doi = 10.1006/bbrc.2000.4149 }} |
||
| ⚫ | * {{cite journal | vauthors = Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN | title = TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription | journal = The Journal of Biological Chemistry | volume = 276 | issue = 48 | pages = 44633–40 | date = November 2001 | pmid = 11572868 | doi = 10.1074/jbc.M107466200 | doi-access = free }} |
||
| ⚫ | * {{cite journal | vauthors = Song CZ, Keller K, Murata K, Asano H, Stamatoyannopoulos G|authorlink5=George Stamatoyannopoulos | title = Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 9 | pages = 7029–36 | date = March 2002 | pmid = 11748222 | pmc = 2808425 | doi = 10.1074/jbc.M108826200 }} |
||
| ⚫ | * {{cite journal | vauthors = Sasaki H, Sato T, Yamauchi N, Okamoto T, Kobayashi D, Iyama S, Kato J, Matsunaga T, Takimoto R, Takayama T, Kogawa K, Watanabe N, Niitsu Y | title = Induction of heat shock protein 47 synthesis by TGF-beta and IL-1 beta via enhancement of the heat shock element binding activity of heat shock transcription factor 1 | journal = Journal of Immunology | volume = 168 | issue = 10 | pages = 5178–83 | date = May 2002 | pmid = 11994473 | doi = 10.4049/jimmunol.168.10.5178 | doi-access = free }} |
||
| ⚫ | * {{cite journal | vauthors = Razzaque MS, Ahmed AR | title = Collagens, collagen-binding heat shock protein 47 and transforming growth factor-beta 1 are induced in cicatricial pemphigoid: possible role(s) in dermal fibrosis | journal = Cytokine | volume = 17 | issue = 6 | pages = 311–6 | date = March 2002 | pmid = 12061838 | doi = 10.1006/cyto.2002.1020 }} |
||
| ⚫ | * {{cite journal | vauthors = Sato K, Yomogida K, Wada T, Yorihuzi T, Nishimune Y, Hosokawa N, Nagata K | title = Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary | journal = The Journal of Biological Chemistry | volume = 277 | issue = 40 | pages = 37678–84 | date = October 2002 | pmid = 12145293 | doi = 10.1074/jbc.M205347200 | doi-access = free }} |
||
| ⚫ | * {{cite journal | vauthors = Rocnik EF, van der Veer E, Cao H, Hegele RA, Pickering JG | title = Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells | journal = The Journal of Biological Chemistry | volume = 277 | issue = 41 | pages = 38571–8 | date = October 2002 | pmid = 12163502 | doi = 10.1074/jbc.M206689200 | doi-access = free }} |
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{{เซอร์ปิน}} |
{{เซอร์ปิน}} |
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{{Posttranslational modification}} |
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รุ่นแก้ไขเมื่อ 09:12, 2 พฤศจิกายน 2564
ฮีทช็อคโปรตีน 47 หรือ เซอร์ปิน เอช1 (อังกฤษ: Heat shock protein 47; HSP47 หรือ SERPINH1) เป็นโปรตีนกลุ่มเซอร์ปินชนิดหนึ่งที่พบในมุษย์ มีบทบาทสำคัญในกระบวนการการสร้างคอลลาเจน ถูกถอดรหัสได้จากยีน SERPINH1 บนโครโมโซมคู่ที่ 11[3][4]
หน้าที่
HSP47 เป็นสมาชิกหนึ่งในโปรตีนมหาวงศ์เซอร์ปิน ทำหน้าที่ยับยั้งการทำงานของเอนไซม์ซีรีนโปรตีเอส การแสดงออกของโปรตีนชนิดนี้สามารถเหนี่ยวนำได้โดยการกระตุ้นเซลล์ให้เกิดความเครียดด้วยความร้อน (heat shock) โดยจะพบการแสดงออกของ HSP47 ในเซลล์ที่มีร่างแหเอนโดพลาซึม ซึ่งเซลล์เหล่านี้จะสร้างและหลั่งคอลลาเจนชนิด I และชนิด II [5] HSP47 จะเคลื่อนที่เข้าไปยัง lumen ของร่างแหเอนโดพลาซึมและเข้าจับกับคอลลาเจน ดังนั้นจึงคาดการณ์ได้ว่า HSP47 เป็นแชพเพอรอนที่ทำหน้าที่เกี่ยวข้องกับการดัดแปลงโมเลกุลของคอลลาเจนให้มีสภาพพร้อมทำงาน อย่างไรก็ตาม ในผู้ป่วยโรคข้ออักเสบรูมาตอยด์อาจพบการแสดงออกของ HSP47 ได้น้อยกว่าปกติ เนื่องจากมีการสร้างสารภูมิต้านทานต้านตนเอง (autoantibody) ต่อ HSP47[3]
อันตรกิริยา
HSP47 สามารถเกิดอันตรกิริยากับคอลลาเจนชนิด I, II, III, IV และ V ได้[6]
อ้างอิง
- ↑ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000149257 - Ensembl, May 2017
- ↑ "Human PubMed Reference:".
- ↑ 3.0 3.1 "Entrez Gene: SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)".
- ↑ Dafforn TR, Della M, Miller AD (December 2001). "The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesis". The Journal of Biological Chemistry. 276 (52): 49310–9. doi:10.1074/jbc.M108896200. PMID 11592970.
- ↑ Williams, R. Sanders (21 March 2000). "Heat Shock Protein 47: A Chaperone for the Fibrous Cap?". Circulation (ภาษาอังกฤษ). 101 (11): 1227–1228. doi:10.1161/01.CIR.101.11.1227. PMID 10725278. สืบค้นเมื่อ 11 December 2017.
- ↑ Mala JG, Rose C (November 2010). "Interactions of heat shock protein 47 with collagen and the stress response: an unconventional chaperone model?". Life Sciences. 87 (19–22): 579–86. doi:10.1016/j.lfs.2010.09.024. PMID 20888348.
แหล่งข้อมูลอื่น
- Razzaque MS, Taguchi T (October 1999). "The possible role of colligin/HSP47, a collagen-binding protein, in the pathogenesis of human and experimental fibrotic diseases". Histology and Histopathology. 14 (4): 1199–212. PMID 10506936.
- Gettins PG (December 2002). "Serpin structure, mechanism, and function". Chemical Reviews. 102 (12): 4751–804. doi:10.1021/cr010170. PMID 12475206.
- Clarke EP, Sanwal BD (January 1992). "Cloning of a human collagen-binding protein, and its homology with rat gp46, chick hsp47 and mouse J6 proteins". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1129 (2): 246–8. doi:10.1016/0167-4781(92)90498-o. PMID 1309665.
- Ikegawa S, Sudo K, Okui K, Nakamura Y (1995). "Isolation, characterization and chromosomal assignment of human colligin-2 gene (CBP2)". Cytogenetics and Cell Genetics. 71 (2): 182–6. doi:10.1159/000134103. PMID 7656593.
- Ikegawa S, Nakamura Y (July 1997). "Structure of the gene encoding human colligin-2 (CBP2)". Gene. 194 (2): 301–3. doi:10.1016/S0378-1119(97)00209-6. PMID 9272875.
- Bekri S, Adélaïde J, Merscher S, Grosgeorge J, Caroli-Bosc F, Perucca-Lostanlen D, Kelley PM, Pébusque MJ, Theillet C, Birnbaum D, Gaudray P (1998). "Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma". Cytogenetics and Cell Genetics. 79 (1–2): 125–31. doi:10.1159/000134699. PMID 9533029.
- Hattori T, Fujisawa T, Sasaki K, Yutani Y, Nakanishi T, Takahashi K, Takigawa M (April 1998). "Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8)". Biochemical and Biophysical Research Communications. 245 (3): 679–83. doi:10.1006/bbrc.1998.8505. PMID 9588174.
- Nagai N, Tetuya Y, Hosokawa N, Nagata K (February 1999). "The human genome has only one functional hsp47 gene (CBP2) and a pseudogene (pshsp47)". Gene. 227 (2): 241–8. doi:10.1016/S0378-1119(98)00592-7. PMID 10023073.
- Hebert C, Norris K, Della Coletta R, Reynolds M, Ordóñez J, Sauk JJ (May 1999). "Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines". Journal of Cellular Biochemistry. 73 (2): 248–58. doi:10.1002/(SICI)1097-4644(19990501)73:2<248::AID-JCB11>3.0.CO;2-A. PMID 10227388.
- Koide T, Aso A, Yorihuzi T, Nagata K (September 2000). "Conformational requirements of collagenous peptides for recognition by the chaperone protein HSP47". The Journal of Biological Chemistry. 275 (36): 27957–63. doi:10.1074/jbc.M003026200. PMID 10862616.
- Hattori T, Takahash K, Yutani Y, Fujisawa T, Nakanishi T, Takigawa M (2001). "Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47". Journal of Bone and Mineral Metabolism. 18 (6): 328–34. doi:10.1007/s007740070004. PMID 11052465. S2CID 35696096.
- Pelletier G, Stefanovsky VY, Faubladier M, Hirschler-Laszkiewicz I, Savard J, Rothblum LI, Côté J, Moss T (November 2000). "Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription". Molecular Cell. 6 (5): 1059–66. doi:10.1016/S1097-2765(00)00104-0. PMID 11106745.
- Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K (January 2001). "Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences". Biochemical and Biophysical Research Communications. 280 (2): 535–40. doi:10.1006/bbrc.2000.4149. PMID 11162551.
- Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN (November 2001). "TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription". The Journal of Biological Chemistry. 276 (48): 44633–40. doi:10.1074/jbc.M107466200. PMID 11572868.
- Song CZ, Keller K, Murata K, Asano H, Stamatoyannopoulos G (March 2002). "Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2". The Journal of Biological Chemistry. 277 (9): 7029–36. doi:10.1074/jbc.M108826200. PMC 2808425. PMID 11748222.
- Sasaki H, Sato T, Yamauchi N, Okamoto T, Kobayashi D, Iyama S, Kato J, Matsunaga T, Takimoto R, Takayama T, Kogawa K, Watanabe N, Niitsu Y (May 2002). "Induction of heat shock protein 47 synthesis by TGF-beta and IL-1 beta via enhancement of the heat shock element binding activity of heat shock transcription factor 1". Journal of Immunology. 168 (10): 5178–83. doi:10.4049/jimmunol.168.10.5178. PMID 11994473.
- Razzaque MS, Ahmed AR (March 2002). "Collagens, collagen-binding heat shock protein 47 and transforming growth factor-beta 1 are induced in cicatricial pemphigoid: possible role(s) in dermal fibrosis". Cytokine. 17 (6): 311–6. doi:10.1006/cyto.2002.1020. PMID 12061838.
- Sato K, Yomogida K, Wada T, Yorihuzi T, Nishimune Y, Hosokawa N, Nagata K (October 2002). "Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary". The Journal of Biological Chemistry. 277 (40): 37678–84. doi:10.1074/jbc.M205347200. PMID 12145293.
- Rocnik EF, van der Veer E, Cao H, Hegele RA, Pickering JG (October 2002). "Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells". The Journal of Biological Chemistry. 277 (41): 38571–8. doi:10.1074/jbc.M206689200. PMID 12163502.
- ฐานข้อมูลออนไลน์ MEROPS สำหรับเปปทิเดส และสารยับยั้งเปปทิเดส: I04.035
- HSP47 Heat-Shock Proteins ในหอสมุดแพทยศาสตร์แห่งชาติอเมริกัน สำหรับหัวข้อเนื้อหาทางการแพทย์ (MeSH)
ลำดับกรดอะมิโน
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MRSLLLLSAF | CLLEAALAAE | VKKPAAAAAP | GTAEKLSPKA | ATLAERSAGL | ||||
| AFSLYQAMAK | DQAVENILVS | PVVVASSLGL | VSLGGKATTA | SQAKAVLSAE | ||||
| QLRDEEVHAG | LGELLRSLSN | STARNVTWKL | GSRLYGPSSV | SFADDFVRSS | ||||
| KQHYNCEHSK | INFRDKRSAL | QSINEWAAQT | TDGKLPEVTK | DVERTDGALL | ||||
| VNAMFFKPHW | DEKFHHKMVD | NRGFMVTRSY | TVGVMMMHRT | GLYNYYDDEK | ||||
| EKLQIVEMPL | AHKLSSLIIL | MPHHVEPLER | LEKLLTKEQL | KIWMGKMQKK | ||||
| AVAISLPKGV | VEVTHDLQKH | LAGLGLTEAI | DKNKADLSRM | SGKKDLYLAS | ||||
| VFHATAFELD | TDGNPFDQDI | YGREELRSPK | LFYADHPFIF | LVRDTQSGSL | ||||
| LFIGRLVRPK | GDKMRDEL |
A: อะลานีน
C: ซิสตีอีน
D: กรดแอสปาร์ติก
E: กลูตาเมต
F: ฟีนิลอะลานีน
G: ไกลซีน
H: ฮีสทิดีน
I: ไอโซลิวซีน
K: ไลซีน
L: ลิวซีน
M: มีไธโอนีน
N: แอสพาราจีน
P: โพรลีน
Q: กลูตามีน
R: อาร์จินีน
S: ซีรีน
T: ทรีโอนีน
V: วาลีน
W: ทริปโตเฟน
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