English: A case of apoptosis (cell death) in an adult cat resulting in gradual depigmentation of skin and fur, making the cat almost completely white over the period of 6 years. Note the slow pigment change around the nose and eyes.
Note this is not an extreme case of slow melanocyte migration to the skin and fur, which makes the cat almost completely white. Melanocyte progression, occurs only in the developing embryo and affects the distriubtion of coloured patches appear on the body surface. In fact the series of images shows progressive pigment loss due to apoptosis (cell death).